Berberine for Anti-aging
Can We Live Forever? Discover the Remarkable Potential of Berberine for Anti-Aging
Every life has a lifespan. The C. elegans worm lives for approximately 14 days. The European lobster gets up to 50 years on earth. The Bristlecone pine tree can live for as long as 5000 years. And humans? Well, we have a maximum lifespan of about 120 years.
Unfortunately, less than thirty percent of us live to celebrate our 100th birthday. And this brings the question – what is it about old age that kills us, and is it treatable?
Luckily, scientists have made significant advancements in the field of anti-aging. In fact, anti-aging experts believe that it won’t be long before they find a way to add 10 to 20 years to human life.
Berberine, a natural dietary supplement, is at the tip of many scientists’ tongues as a promising remedy for boosting longevity and promoting healthy aging.
If you’ve not heard of Berberine before, let’s get you acquainted with this incredible ingredient and its remarkable potential.
What is Berberine?
Berberine is a plant alkaloid found in several plants, including Oregon grape, European barberry, Tree turmeric, Goldenseal, Goldthread, and Phellodendron.
Ancients, especially in Chinese and Ayurvedic medicine, have used the plants named above to treat various conditions, mostly intestinal ailments and blood-related complications that resulted from low-insulin sensitivity.
And What Causes Aging Anyway?
Aging is a result of the biological accumulation of damage to our cells.
Scientists suggest that getting old is the primary risk factor for human diseases because it causes:
- Cellular growth arrest
- Impaired tissue function
- Compromised metabolism
Signs of Aging
We all age at different rates and to different degrees, but we show many common aging effects. Some of the common signs and symptoms of old age include;
- Hearing loss
- Poor eyesight
- Weakened muscles
- Slow heart rate hi
- High blood pressure
- Decreased mental agility
- Reduced immunity
High Blood Sugar Is Linked to Aging and Disease
According to a study published by researchers at Columbia University Medical Center, maintaining your blood sugar levels even in the absence of disease might be a crucial strategy for preserving cognitive health.
Besides, science shows that consuming too many metabolically active dense carbohydrates accelerates aging and increases your disease susceptibility.
See, each time you eat carbs, your blood sugar level increases. And as the insulin sensitivity theory suggest, your blood glucose tends to increase as you age, and insulin becomes less and less effective at lowering it.
As a result, the excess sugars in your blood causes proteins to stick together, thereby damaging their function. For instance, excess blood glucose is more likely to react with collagen (a protein in the skin), causing brown spots (aka age spots), premature wrinkling, and loss of skin elasticity.
Interestingly, these sugar-damaged, highly dangerous cross-linked proteins are called Advanced Glycation End products, or AGE.
Check out some more examples of how AGE (Advanced Glycation End-products) can lead to premature aging.
- Excess blood glucose might damage the proteins in your eyes’ lenses, causing cataracts and possible blindness
- If the protein-sugar complex damages the collagen in your arteries, fatty plaques might occur
- If the collagen in your connective tissue cross-links with excess sugar, arthritis could occur
- Glycation (sugar damaged proteins) might destroy nerve cells in the brain, causing Alzheimer’s and other neurodegenerative diseases
- Glycation stimulates the formation of free radical molecules, which fast-track aging and increase the risk of disease
Current Medical Practices Are Ineffective Against Age-related Diseases
Today’s medical practitioners use the infectious disease model to treat all illnesses. Sadly, this approach isn’t effective against age-related ailments, which have different root causes.
When you get sick, the physician uses everything in the medical armory to treat your symptoms. Consequently, you feel better, get on with life, until the next time you’re ill, and your physician will repeat the procedure.
That’s an excellent way to fight infectious diseases; it has significantly helped increase life expectancy during the last century. But it’s an ineffective way of treating age-related chronic disease.
The damage aging causes is a continuous process, and treating the symptoms achieves very little and ultimately doesn’t cure the related disease. That’s why senior citizens often have multiple chronic ailments and must take several drugs to manage them.
Rejuvenation biotechnology is a multi-disciplinary approach that aims to prevent age-related disease by targeting the aging process. Consequently, it might be possible to keep tissues and organs biologically younger and healthier, thereby reversing the age-related decline.
Researchers in this field have taken a keen interest in Berberine because of its ability to prevent age-related decline and promote healthy aging.
Berberine Reduces Aging. But How?
Berberine tricks the body into thinking that it is calorie-deficient.
In one anti-aging study, scientists doubled the lifespan of a C. elegans worm by causing it to absorb fewer nutrients. The scientists did this by knocking out DAF-2, a gene that regulates insulin, basically tricking the worm’s body to think it was fasting.
But how does starvation increase lifespan?
Well, your body needs insulin to help it absorb nutrients. If you have less insulin or have an insulin receptor that doesn’t work as well, your body thinks that it doesn’t have enough food.
If the body isn’t getting enough calories, it must ensure that it uses its energy sparingly, as it prepares for difficult times.
As such, it slows down cell division, doing it only when it’s necessary. This is great because our chromosomes have protective caps known as telomeres, which shorten every time our cells divide. When the telomeres are depleted, the cell dies, ultimately accelerating aging.
Another remarkable effect of tricking the body that it is low on food reserves is that it folds its proteins efficiently.
Finally, Berberine activates the AMPK (adenosine monophosphate-activated protein kinase), an enzyme that regulates energy intake and uptake in the cells. As a result, it reduces mTOR, which ultimately reduces the rate of cell division and protein synthesis.
You’ll love to know that Berberine follows similar action mechanisms with metformin, a prescription drug for diabetes, and possibly the first-ever anti-aging drug.
So, Can We Live Forever?
Is that what you want? To live forever? If you’ve watched Star Wars, you know it’s not all that cool.
Anyway, sorry to burst your bubble. Everything has a lifespan. The excellent news is that aging research is developing fast, especially with the discovery that the rate of aging is controlled, partly to some extent by genetic pathways and biological processes conserved in evolution.
Berberine, a plant alkaloid, can affect some of these pathways, showing promise as a useful supplement for increasing longevity and promoting healthy aging.
The prospect of living up to a century of healthy years sounds good to me. How about you?
Check out our Berberine supplements at our shop, and let’s live to an infinite age together.