Berberine - The Blood Sugar Balancing
Hail Berberine; A Natural Remedy for Diabetes that you Won’t See on the News or Advertised on your Screen
I'm fading. I need an energy bar. I need chocolate. I've got to boost my blood sugar.
We're sorry if that sounds familiar, and it sucks even more that one in every ten Americans know this harsh reality too well – and that number keeps soaring.
What if these conditions, usually termed as chronic, were reversible? Wait. What? You mean a chance to get off the blood sugar roller coaster? Forever?
Yes. There's a way you can regulate your blood sugar naturally, without risking adverse effects, and at a tiny fraction of the average cost associated with treating diabetes.
You'll also love to know that Berberine stands up pretty well to scrutiny, and its blood sugar balancing effects are backed by science.
Before we delve deeper into analyzing how this miraculous ingredient can regulate your blood sugar, let’s address the elephant in the room.
Diabetes mellitus (DM) is a metabolic disorder that affects the endocrine system. Statistics from the International Diabetes Federation show that in 2013, roughly 382 million people were diagnosed with this condition globally. Even worse, the numbers were predicted to rise to 592 million by 2035.
Type 2 diabetes mellitus is the predominant form of DM that accounts for 95% of diabetes patients globally.
The standard treatment for type 2 diabetes includes a balanced diet, regular exercise, use of oral hypoglycemic drugs, and subcutaneous injections. While scientists have made significant progress in the field of anti-diabetes medication, some limitations still exist.
For years, science hasn’t been able to provide medication that could maintain stable blood sugar control. Besides, more patients are wary of the potential toxicity and side effects of anti-diabetic drugs, like bone loss, weight gain, and elevated risk of cardiovascular conditions.
Metformin, perhaps the most promising drug in this category, causes gastrointestinal discomfort and kidney damage. Pioglitazone, another one, is said to increase the risk of edema, bladder cancer, and distal bone fractures in post-menopausal women.
Natural medicines have the advantage of holistic regulation, which may control bodily functions through multiple mechanisms, thus being more effective in alleviating metabolic disorders, and improving diabetic symptoms, and, ultimately, the quality of life.
What's more, herbal remedies are less toxic and have little to zero side effects, not to mention more affordable than Western medicine.
With that said, shouldn’t herbal remedies be thought of as a better alternative or at least a supplement to Western medication for regulating blood sugar? That way, we can address this diabetes menace from its core, once and for all.
Berberine, a natural remedy, has aroused significant interest due to its blood sugar balancing powers. Even better, it has proven considerably useful in the treatment of various diabetic conditions (diabetic nephropathy, diabetic neuropathy, and diabetic cardiomyopathy).
What is Berberine?
Berberine is a naturally occurring alkaloid found in the roots, rhizome, and stem bark of plants such as Oregon grape, Goldenseal, Goldthread, Barberry, and Tree turmeric.
Plant alkaloids are a category of active compounds proven to have various psychological effects on humans and have been adopted into Western medicine, the most well-known being ephedrine and morphine.
Berberine is believed to have a wide range of therapeutic powers, including antimicrobial, antioxidative, and anti-inflammatory properties.
Many health-conscious people, especially those outside the scientific and homeopathic communities, are intrigued by Berberine as it's not as recognizable as other antioxidants like turmeric and resveratrol. Like turmeric, Berberine has a deep, vibrant yellow color.
History of Berberine
The barberry fruit, one source of Berberine, was first recorded on the tablet of an Assyrian emperor from 650 B.C. as a blood purifying agent.
Berberine, in itself, has been used in Chinese and Native American healing practices for well over centuries and millennia in Ayurvedic medicine.
In Ayurvedic medicine, Berberine is used to treat various health problems, from soothing hemorrhoids and indigestion to reducing obesity and dysentery.
The more carbs you ingest, the more insulin is secreted to facilitate absorption – well, until the cells have had enough glucose.
Sometimes, the pancreas is unable to produce sufficient amounts of insulin or cells are insulin-resistant, which is termed as blood sugar imbalance. This condition affects millions of individuals globally.
According to a 2017 report from the Center for Disease Control and Prevention, a whopping 100 million Americans were either diabetic or pre-diabetic.
“Diabetes is when your blood glucose (blood sugar) levels are higher than expected. This rise is mostly attributed to consuming carbohydrates such as cereals, bread, rice, pasta, and desserts” Maggie Powers, Ph.D., RD, CDE, and diabetes expert.
Scientific evidence reveals that Berberine is as effective at balancing blood sugar as the diabetes drug, metformin, but with no adverse effects.
If you’re diagnosed with pre-diabetes or diabetes, metformin is the first medication an American doctor will prescribe to you. Although a relatively safe drug, prolonged metformin usage can cause kidney damage and gastrointestinal discomfort.
What's more, Berberine is normoglycemic, which means that it will only lower blood sugar when it’s already high.
Overall, Berberine lowers blood sugar, fasting insulin, post-meal blood sugar, and HbA1c by boosting the number of insulin receptors.
Besides balancing blood sugar, Berberine can reduce triglycerides, LDL cholesterol, and blood pressure – something metformin doesn’t do.
How cool is Berberine? Not only does it provide a natural remedy for diabetic and pre-diabetic individuals, but it can also help patients with full-blown metabolic syndrome!
Read on to discover how Berberine wields its blood balancing superpowers.
How does Berberine Regulate Blood Sugar?
- Berberine activates AMPK (adenosine monophosphate kinase), also known as the ‘metabolic master switch’ due to its ability to influence metabolism. AMPK is an energy-stabilizing enzyme found within the cells. The enzyme boosts autophagy, which increases insulin sensitivity at the cellular level by encouraging internal repair.
- It slows down the sugar factory. Studies indicate that Berberine stimulates glycolysis, the process through which the body breaks down sugar, and may inhibit gluconeogenesis, the process of creating glucose. These activities reduce insulin sensitivity and help to regulate blood sugar.
- Berberine neutralizes the effects of NADPH oxidase. Inhibiting this enzyme is a therapeutic target for future diabetes medications. NADPH oxidase causes oxidative stress, leading to vascular problems like arteriosclerosis in people with type 2 diabetes.
- Berberine boosts thermogenesis. As a result, it enhances insulin sensitivity and reduces the liver’s glucose production. Similar to metformin, Berberine impedes the liver’s tendency to make new glucose when its cells become resistant to insulin.
- It modulates the gut microbiota. Berberine kills off the harmful bacteria in your gut and promotes good bacteria, thereby reducing inflammation and improving blood sugar balance. Since the ingredient is poorly absorbed in the stomach, it travels to the end of your digestive tract, where probiotics gather, killing off bad bacteria, which is useful against diabetes and other conditions.
- It promotes the secretion of intestinal glucagon-like protein-1 (GLP-1). This peptide has numerous antidiabetic effects that make it useful for patients with type 2 diabetes. They include potentiation of glucose-stimulated insulin, gastric emptying, inhibition of glucagon release, and enhancement of β-cell growth and survival.
- Berberine upregulates hepatic low-density lipoprotein receptor mRNA expression. As such, it prevents insulin resistance and metabolic syndrome.
- It increases glucose transporters, a group of membrane proteins that facilitate the transport of blood sugar across the plasma membrane, thus reducing insulin sensitivity.
How does it feel now, knowing that you aren’t doomed or destined to live on the blood sugar roller coaster for the rest of your life?
Before that fire dies, why don’t you take a minute to check out Infinite Age Berberine supplements? Something else besides the price-tag could make your day even better!